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High concernSolvent

1,4-Dioxane

Possible carcinogenEnvironmental persistence

What it is

A cyclic ether used as an industrial solvent and an unintentional contaminant of ethoxylated ingredients.

What it does

Not added intentionally to cosmetics; formed as a byproduct of ethoxylation used to make PEGs, polysorbates, and laureth surfactants.

Why it’s a concern

Classified by US EPA as a likely human carcinogen and by IARC as Group 2B. Never declared on ingredient lists because it is a contaminant. New York state has required finished personal care products to contain no more than 2 ppm 1,4-dioxane as of 2023. Persistent in groundwater and drinking water.

Also known as

diethylene dioxidediethylene ether

CAS numbers

123-91-1

Commonly found in

shampoobody washliquid laundry detergentdish soap

Safer alternatives

  • non-ethoxylated surfactants
  • products tested to NY 2 ppm cap

Related chemical families

Vocs

Sources

  • US EPA IRIS 1,4-Dioxane
  • IARC Volume 71