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Untoxed HealthUntoxedHealth
High concernAntimicrobial

Benzalkonium Chloride

AllergenSkin irritant

What it is

A quaternary ammonium cationic surfactant used as an antiseptic and preservative.

What it does

Disinfectant and preservative in eye drops, cleaning wipes, hand sanitizers, and nasal sprays.

Why it’s a concern

Known respiratory sensitizer; occupational asthma cases are documented among cleaning workers. Prolonged use in eye drops can damage corneal epithelium. FDA reclassified it in the 2016 antiseptic rule and continues to require safety data for OTC use.

Also known as

BACADBACalkyldimethylbenzylammonium chloride

CAS numbers

8001-54-563449-41-2

Commonly found in

hand sanitizercleaning wipeseye dropsnasal spray

Safer alternatives

  • alcohol-based sanitizer
  • preservative-free eye drops

Sources

  • FDA OTC Topical Antiseptic Rule
  • Purohit et al. 2000, American Journal of Industrial Medicine