High concernPlasticizer
Di(2-ethylhexyl) phthalate
PhthalateEndocrine disruptorReproductive toxicantPossible carcinogen
What it is
A high-molecular-weight ortho-phthalate ester used for decades to soften PVC plastics. It is an oily, colourless liquid that migrates readily from plastic into fats, oils, and saliva.
What it does
Flexibilises PVC in medical tubing, food packaging, flooring, and toys. Not typically added to cosmetics today but can contaminate fragranced products via packaging.
Why it’s a concern
DEHP is classified by IARC as Group 2B (possibly carcinogenic to humans) and is a known anti-androgen. The US CDC NHANES biomonitoring program detects DEHP metabolites in nearly all Americans tested. It is banned above 0.1% in children’s toys in the EU, US, and many other jurisdictions because of fetal testicular effects observed in rodent studies (the phthalate syndrome).
Also known as
DEHPbis(2-ethylhexyl) phthalatedioctyl phthalateDOP
CAS numbers
117-81-7
Commonly found in
vinyl flooringmedical IV bagsshower curtainsfood packaging
Safer alternatives
- DINCH
- citrate-based plasticizers
- silicone medical tubing
- glass containers
Related chemical families
Sources
- IARC Monograph Volume 101
- US CDC NHANES Biomonitoring