Untoxed HealthUntoxedHealth
← All ingredients
Medium concernFragrance

Galaxolide

Endocrine disruptorEnvironmental persistence

What it is

A polycyclic musk, one of the most widely used synthetic musks globally.

What it does

Provides a soft, clean musk scent in perfumes, laundry detergents, and fabric softeners.

Why it’s a concern

Galaxolide is persistent, has been detected in surface water, sediment, fish, and human blood and breast milk. Studies suggest it can interfere with cellular efflux pumps that protect against xenobiotics (Luckenbach and Epel 2005, Environmental Health Perspectives). Its lipophilic nature promotes bioaccumulation in aquatic food webs.

Also known as

HHCB1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran

CAS numbers

1222-05-5

Commonly found in

perfumelaundry detergentfabric softener

Safer alternatives

  • macrocyclic musks with better biodegradability
  • fragrance-free products

Related chemical families

Synthetic Fragrance

Sources

  • Luckenbach and Epel 2005, EHP