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Medium concernUV filter

Octisalate

AllergenEndocrine disruptor

What it is

A salicylate UVB filter used to enhance photostability and absorb short UV wavelengths.

What it does

Chemical UV filter in sunscreens, often combined with avobenzone and homosalate.

Why it’s a concern

Demonstrated systemic absorption above FDA safety-review thresholds in the 2020 MUsT study. In vitro data suggest weak endocrine activity. Allergic contact dermatitis is reported but uncommon. Restricted in some EU formulas pending further evaluation of aggregate salicylate exposure.

Also known as

ethylhexyl salicylate2-ethylhexyl salicylate

CAS numbers

118-60-5

Commonly found in

sunscreenspf lip balm

Safer alternatives

  • non-nano zinc oxide
  • non-nano titanium dioxide

Sources

  • Matta et al. 2020, JAMA