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Untoxed HealthUntoxedHealth
High concernPlasticizer

Dibutyl phthalate

PhthalateEndocrine disruptorReproductive toxicant

What it is

A short-chain ortho-phthalate diester, colorless oily liquid with mild aromatic odor.

What it does

Provides flexibility and film-forming properties. Historically used in nail polish to prevent chipping and in fragrance formulations as a solvent.

Why it’s a concern

DBP is classified by the EU as a presumed human reproductive toxicant. Some human cohorts associate prenatal DBP biomarkers with cognitive or language outcomes, but the evidence is observational and not consistently replicated. EPA's TSCA unreasonable-risk finding applies to specific conditions of use and does not cover food contact or cosmetics.

Factor-Litvak P 2014 | human cohortBornehag CG 2018 | human cohortUS EPA 2026 | regulatory assessment

Also known as

DBPdi-n-butyl phthalatebutyl phthalate

CAS numbers

84-74-2

Commonly found in

nail polishfragrancehair spray

Safer alternatives

  • 5-free or 10-free nail polish formulas
  • acetyl tributyl citrate

Related chemical families

Phthalates

Sources

  • EU CLP Classification
  • California Proposition 65 List